Scientific Study Published in the U.S. Library of Medicine
A hundred and fourteen women aged 45 -65 years were randomized to receive 2.5 grams of BCP (Bioactive Collagen Peptides) or placebo, once daily for 8 weeks, with 57 subjects allocated to each group. Skin wrinkles were objectively measured in all subjects before starting the treatment, as well as 4 and 8 weeks after the last intake. A subgroup was established for suction blister biopsies analyzing procollagen I, elastin and fibrillin at the beginning of the treatment and after 8 weeks of intake. The ingestion of the specific bioactive collagen peptide (bcp) used in this study promoted a statistically significant reduction of eye wrinkle volume (p < 0.05) in comparison to the placebo group after 4 and 8 weeks (20%) of intake. Moreover a positive long-lasting effect was observed 4 weeks after the last BCP administration. Additionally, after 8 weeks of intake a statistically significantly higher content of procollagen type 1 (65%) and elastin (18%) in the BCP-treated volunteers compared to the placebo-treated patients was detected.
How it works
The specific peptides are recognized by fibroblast cells in the dermal layer of the skin as collagen fragments like those resulting from catabolic activities. Therefore they are stimulated to increase collagen production to counter-balance the pretend collagen degradation in the dermis. The result is a considerably higher production of dermal collagen and overall extracellular matrix, replacing what is lost through aging and the environment.